Mechanisms mediating NTS P2x receptor-evoked hypotension: cardiac output vs. total peripheral resistance

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mechanisms mediating NTS P2x receptor-evoked hypotension: cardiac output vs. total peripheral resistance.

We have previously shown that P2x purinoceptor activation in the subpostremal nucleus tractus solitarius (NTS) produces dose-dependent decreases in mean arterial pressure (MAP), heart rate, efferent sympathetic nerve activity, and significant peripheral vasodilation. However, the relative roles of cardiac output (CO) and total peripheral resistance (TPR) in mediating this depressor response are...

متن کامل

Cardiac output and total peripheral resistance in carotid sinus reflex.

SCHMIDT,ROBERT M., MAMORU KUMADA, AND KIICHI SAGAWA. Cardiac output and total peripheral resistance in carotid sinus reflex. Am. J. Physiol. 221(Z) : 480-487. 197 1 .-The sensitivity of the carotid sinus baroreceptor reflex to step change in sinus pressure was studied in anesthetized dogs, with emphasis on the relative contributions of cardiac output (CO) and total peripheral resistance (TPR) i...

متن کامل

Cardiac output and total peripheral resistance in spontaneously hypertensive rats.

ESPITE extensive studies on spontaneously hypertensive rats, there have been no studies on the cardiac output except a preliminary work by Albrecht et al,4) which reported a decreasing tendency of cardiac output with age. These authors employed the Stewart-Hamilton principle for the measurement of cardiac output. An attempt was made in this study to measure cardiac output in SHR by applying an ...

متن کامل

Fundamental hemodynamic mechanisms mediating the response to myocardial ischemia in conscious paraplegic mice: cardiac output versus peripheral resistance

Autonomic dysfunction, a relative sedentary lifestyle, a reduced muscle mass and increased adiposity leads to metabolic abnormalities that accelerate the development of coronary artery disease (CAD) in individuals living with spinal cord injury (SCI). An untoward cardiac incident is related to the degree of CAD, suggesting that the occurrence of a significant cardiac event is significantly high...

متن کامل

Cardiac Output and Totl4l Peripheral Resistance in Post-hemorrhagic Hypotension and Shock1

The anesthetized dog when submitted to a prolonged period of drastic hypotension, achieved by controlled bleeding, enters into a state of irreversible shock. The standard procedure developed in this laboratory for producing this state (1) ent!ails lowering the arterial blood pressure by rapid bleeding to 50 mm. of Hg and sustaining it at this level for 90 minutes; it is then reduced to 30 mm. o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology

سال: 2001

ISSN: 0363-6135,1522-1539

DOI: 10.1152/ajpheart.2001.281.5.h2198